114: The Ratio of Colony Forming Unit (CFU) to Total Nucleated Cell (TNC) Count Predicts Engraftment in Umbilical Cord Blood Transplant
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منابع مشابه
Assessment of Umbilical Cord Nucleated Red Blood Cell Count in Discharged and Dead Very Low Birth Weight Infants
Background: Predictive value of the umbilical nucleated red blood cells (NRBCs) at birth for neonatal outcomes has been assessed. Hence, the present study was conducted to compare NRBC between discharged and dead neonates.Methods: This cross-sectional study was performed on preterm newborns with a birth weight of < 1,500 g admitted to the Neonatal Intensive Care Unit of Ghaem Hospital, Ma...
متن کاملFeasibility of Collecting Umbilical Cord Blood in Jordan and the Effect of Maternal and Neonatal Factors on Hematopoietic Stem Cell Content
BACKGROUND Cord blood transplant is an accepted treatment for many malignant and non-malignant diseases. We sought to determine the feasibility of collecting cord blood in Jordan and the effect of maternal and fetal factors on the quality of the cord blood units. METHODS A total of 124 cord blood units were collected, and 75 (60%) cord blood units were included in this analysis. Cord blood vo...
متن کاملPlacental/umbilical cord blood for unrelated-donor bone marrow reconstitution: relevance of nucleated red blood cells.
Placental/umbilical cord blood (PCB) is a source of hematopoietic stem cells for bone marrow reconstitution. Engraftment speed and survival are related to the total nucleated cell (TNC) dose of the graft. This study explored the possible influence on engraftment of nucleated red blood cells (NRBCs) in the graft. Automated hematology analyzers were used to enumerate TNCs. NRBCs were counted by v...
متن کاملMild hypoxia and human bone marrow mesenchymal stem cells synergistically enhance expansion and homing capacity of human cord blood CD34+ stem cells
Objective(s): Cord blood (CB) is known as a valuable source of hematopoietic stem cells (HSC). Identifying strategies that enhance expansion and maintain engraftment and homing capacity of HSCs can improve transplant efficiency. In this study, we examined different culture conditions on ex vivo expansion and homing capacity of CB-HSCs. Materials and Methods: In this study, 4-5 different units o...
متن کاملبررسی فراوانی سلول های بنیادی خونساز نمونه های پیوند خون محیطی نگهداری شده در دمای 4°C تا هشت روز پس از جمع آوری نمونه ها
Background: Hematopoietic stem cell (HSC) transplantation has brought the possibility of the use of high dose chemotherapy in the treatment of malignant hematopoietic diseases. Short-term HSC preservation at 4˚C is the most common method for autologous peripheral blood stem cell transplantation (PBSCT). Materials and Methods: Thirty-seven mobilized PBSC samples from thirteen hematological pat...
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ژورنال
عنوان ژورنال: Biology of Blood and Marrow Transplantation
سال: 2008
ISSN: 1083-8791
DOI: 10.1016/j.bbmt.2007.12.123